Monday, February 16, 2009

Pharmacokinetics of paxil

Paxil
Operating matter: Paxil* (Paroxetine*)Pharmacological groups: Antidepressants
Composition and form of issue: Pills of 1 tabl.paroksetina gidrokhlorid of gemigidrat is 22,8 mgs(20,0 mgs of paroksetina are equivalent)auxiliary matters: calcium of digidrofosfat digidrat; karboksimetilkrakhmal sodium type And; magnesium stearatshell of pill:
Opadry white YS-1R-7003 (gipromelloza, titan dioxide, makrogol 400, polisorbat 80)
there is 10 sht in blistere.; in a box 1, 3 or 10 blisterov.

Description of medicinal form: White biconvex pills, tunicate, oval form with engraving "20" on one side and by the line of break a secret on other.Description: Selective ingibitor of reverse capture of serotonin.

Pharmacological action: to readClinical pharmacology: Adopting paroksetina at mornings does not have unfavorable influence on quality and duration of sleep. In addition, as far as the display of effect of treatment of paroksetinom, sleep can be improved. At the use of sleeping-pills of short action in combination with antidepressants the additional effects of sides did not arise up.In a few first weeks of therapy of paroksetin effectively diminishes the symptoms of depression and suitsidal'nye idea. The results of researches in which patients adopted paroksetin on an extent to 1 year showed that preparation prevented the relapses of depression effectively.

The controlled clinical researches of paroksetina at treatment of depression for children and teenagers (7–17 years) did not prove his efficiency, therefore preparation is not shown for treatment of the indicated age group.Paroksetin is effective at treatment of obsessivno-kompul'sivnogo disorder (OKR) at adults, and also for children and teenagers in age 7–17 years.It is set that at treatment of panicky disorder at adults combination of paroksetina and kognitivno-povedencheskoy therapy meaningfully more effective, than one kognitivno-povedencheskaya therapy.Researches showed that paroksetin possessed insignificant ability ingibirovat' антигипертензивные effects of guanetidina.

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